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課程名稱 |
近代腫瘤生物學特論Ⅱ
Modern Tumor Biology Ⅱ |
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開課學期 |
106-2 |
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授課對象 |
醫學院 腫瘤醫學研究所 |
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授課教師 |
歐大諒 |
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課號 |
Onco8014 |
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課程識別碼 |
453 D0150 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期五9,10(16:30~18:20) |
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上課地點 |
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備註 |
本課程中文授課,使用英文教科書。上課地點：基因體5樓會議室。與郭遠燁、張純榮、曾奕軒、邵幼雲、曾士傑、蘇聖芳合授
總人數上限：20人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1062Onco8014_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
This course is designed to be an introductory course for those who are interested in understanding oncogenesis. The course will cover several issues including epigenetics, tumor angiogenesis, immunosurveillance, immune escape and inflammation in the process of malignant transformation. Some materials, like cell cycle and chemical carcinogenesis, will not be explained in full detail but will be reviewed briefly. Those who have taken one basic course in tumor biology and graduate students from non-oncology backgrounds are welcome. |
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課程目標 |
Topics to be covered:
1. Tumor suppression genes and oncogene.
2. Transcriptional factors and tumorigenesis.
3. DNA methylation , histone modification and chromatin remodelling in cancer.
4. Angiogenesis in life, tumor and medicine.
5. Immunosurveillance and immune escape of cancer.
6. Inflammation and cancer.
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課程要求 |
待補 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
John, M., Peter, M. H., Mark, A. I., Joe, W. G., & Craig, B. T.(2008). The Molecular Basis of Cancer. Philadelphia: Saunders Elsevier. |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
3/02 |
蘇聖芳老師 |
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第2週 |
3/09 |
Inflammation and cancer II - stromal - cancer interaction in the microenvironment - 張純榮老師 |
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第3週 |
3/16 |
Tumor mesenchymal/stromal environment and agiogenesis - 曾奕軒老師 |
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第5週 |
3/30 |
Understanding and using information about cancer genomes - 郭遠燁 老師 |
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第7週 |
4/13 |
Cancer therapeutics; Heat shock protein 90 and proteasome - 歐大諒 老師 |
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第8週 |
4/20 |
Phase I trials today - 曾士傑老師 |
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第15週 |
6/08 |
The molecular Pathogenesis of head and neck cancer; ER stress and cancer - 歐大諒老師 |
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第16週 |
6/15 |
RNA as a therapeutic molecular - 曾士傑 老師 |
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第17週 |
6/22 |
Natural and Acquired Resistance to Cancer Therapies - 蘇聖芳老師 |
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